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Long‐term outcomes of biologic therapy for the treatment of prepouch ileitis: A multi‐centre multi‐national retrospective study

Prepouch ileitis (PPI) is inflammation of the ileum proximal to an ileoanal pouch, usually associated with pouchitis. The treatment of PPI as a specific entity is poorly studied, and long‐term… Click to show full abstract

Prepouch ileitis (PPI) is inflammation of the ileum proximal to an ileoanal pouch, usually associated with pouchitis. The treatment of PPI as a specific entity is poorly studied, and long‐term follow‐up data are lacking. We aimed to describe the long‐term outcomes of biologic therapy in a large, multi‐centre, multi‐national cohort of patients with PPI.

Keywords: outcomes biologic; biologic therapy; term outcomes; term; long term; prepouch ileitis

Journal Title: Colorectal Disease
Year Published: 2025

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