Amniotic fluid‐derived stem cells (AFSCs) possessing multilineage differentiation potential are proposed as a novel and accessible source for cell‐based therapy and tissue regeneration. Glial‐derived neurotrophic factor (GDNF) has been hypothesized… Click to show full abstract
Amniotic fluid‐derived stem cells (AFSCs) possessing multilineage differentiation potential are proposed as a novel and accessible source for cell‐based therapy and tissue regeneration. Glial‐derived neurotrophic factor (GDNF) has been hypothesized to promote the therapeutic effect of AFSCs on markedly ameliorating renal dysfunction. The aim of this study was to investigate whether AFSCs equipped with GDNF (GDNF‐AFSCs) had capabilities of attenuating mouse renal tubular epithelial cells (mRTECs) apoptosis and evaluate its potential mechanisms.
Journal Title: Cell Proliferation
Year Published: 2018
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