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Induction of secondary necrosis/pyroptosis contributes to the toxicity of chemotherapeutic drugs, in which gasdermin E (GSDME) plays critical roles. This study aimed to explore whether GSDME is involved in mediating… Click to show full abstract
Induction of secondary necrosis/pyroptosis contributes to the toxicity of chemotherapeutic drugs, in which gasdermin E (GSDME) plays critical roles. This study aimed to explore whether GSDME is involved in mediating the cytotoxic effects of cisplatin and doxorubicin on mouse macrophages.
Keywords:
caspase mediated;
mouse macrophages;
cisplatin doxorubicin;
secondary necrosis
Journal Title: Cell Proliferation
Year Published: 2019
Link to full text (if available)
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Journal Title: Cell Proliferation
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!