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Mechanical force modulates periodontal ligament stem cell characteristics during bone remodelling via TRPV4

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Mechanical force plays an important role in modulating stem cell fate and behaviours. However, how periodontal ligament stem cells (PDLSCs) perceive mechanical stimulus and transfer it into biological signals, and… Click to show full abstract

Mechanical force plays an important role in modulating stem cell fate and behaviours. However, how periodontal ligament stem cells (PDLSCs) perceive mechanical stimulus and transfer it into biological signals, and thereby promote alveolar bone remodelling, is unclear.

Keywords: periodontal ligament; stem cell; mechanical force; stem; ligament stem; cell

Journal Title: Cell Proliferation
Year Published: 2020

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