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In contrast to extensive studies on bone metastasis in advanced prostate cancer (PCa), liver metastasis has been under‐researched so far. In order to decipher molecular and cellular mechanisms underpinning liver… Click to show full abstract
In contrast to extensive studies on bone metastasis in advanced prostate cancer (PCa), liver metastasis has been under‐researched so far. In order to decipher molecular and cellular mechanisms underpinning liver metastasis of advanced PCa, we develop a rapid and immune sufficient mouse model for liver metastasis of PCa via orthotopic injection of organoids from PbCre+; rb1f/f;p53f/f mice.
Keywords:
prostate cancer;
metastasis;
model liver;
liver metastasis;
mouse model
Journal Title: Cell Proliferation
Year Published: 2021
Link to full text (if available)
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Journal Title: Cell Proliferation
Year Published: 2021
Link to full text (if available)
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recommendations!