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The individual differences and pervasive resistance seriously hinder the optimization of irinotecan‐based therapeutic effectiveness. Eukaryotic translation initiation factor 3a (eIF3a) plays a key role in tumour occurrence, prognosis and therapeutic… Click to show full abstract
The individual differences and pervasive resistance seriously hinder the optimization of irinotecan‐based therapeutic effectiveness. Eukaryotic translation initiation factor 3a (eIF3a) plays a key role in tumour occurrence, prognosis and therapeutic response. This study focused on the role of eIF3a in irinotecan‐induced DNA damage response.
Keywords:
dna damage;
eif3a;
induced dna;
response;
irinotecan induced;
damage response
Journal Title: Cell Proliferation
Year Published: 2022
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Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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recommendations!