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Telomere shortening impairs alveolar regeneration

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Short telomeres in alveolar type 2 (AT2) cells have been associated with many lung diseases. The study aimed to investigate the regeneration capacity of AT2 cells with short telomeres by… Click to show full abstract

Short telomeres in alveolar type 2 (AT2) cells have been associated with many lung diseases. The study aimed to investigate the regeneration capacity of AT2 cells with short telomeres by knocking out Tert in mice (G4 Tert−/−) from the whole to the cellular level.

Keywords: regeneration; telomere shortening; shortening impairs; impairs alveolar; alveolar regeneration

Journal Title: Cell Proliferation
Year Published: 2022

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