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Mesangial cell proliferation is the most basic pathological feature of immunoglobulin A nephropathy (IgAN); however, the specific underlying mechanism and an appropriate therapeutic strategy are yet to be unearthed. This… Click to show full abstract
Mesangial cell proliferation is the most basic pathological feature of immunoglobulin A nephropathy (IgAN); however, the specific underlying mechanism and an appropriate therapeutic strategy are yet to be unearthed. This study aimed to investigate the therapeutic effect of triptolide (TP) on IgAN and the mechanism by which TP regulates autophagy and proliferation of mesangial cells through the CARD9/p38 MAPK pathway.
Keywords:
cell proliferation;
card9 p38;
proliferation;
mesangial cell;
p38 mapk
Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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recommendations!