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The main target of current drugs for alleviating bone loss is osteoclasts. However, the long‐term application of such drugs will also cause side effects. Therefore, it is of great need… Click to show full abstract
The main target of current drugs for alleviating bone loss is osteoclasts. However, the long‐term application of such drugs will also cause side effects. Therefore, it is of great need to develop new and safer therapeutics for osteoporosis. In recent years, drug development based on gut microbiota has gradually attracted attention. This manuscript investigates the inhibitory effect of urolithin B (UB) on osteoclastogenesis and differentiation in vitro and in ovariectomized (OVX) mice.
Keywords:
urolithin suppressed;
osteoclast activation;
loss;
bone loss;
activation reduced;
suppressed osteoclast
Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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recommendations!