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Spatial transcriptomic profiling to identify mesoderm progenitors with precision genomic screening and functional confirmation

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Mesoderm, derived from a new layer between epiblast and hypoblast during gastrulation, can differentiate into various tissues, including muscles, bones, kidneys, blood, and the urogenital system. However, systematic elucidation of… Click to show full abstract

Mesoderm, derived from a new layer between epiblast and hypoblast during gastrulation, can differentiate into various tissues, including muscles, bones, kidneys, blood, and the urogenital system. However, systematic elucidation of mesoderm characteristics and specific markers remains a challenge. This study aims to screen and identify candidate genes important for mesoderm development.

Keywords: mesoderm progenitors; identify mesoderm; progenitors precision; transcriptomic profiling; profiling identify; spatial transcriptomic

Journal Title: Cell Proliferation
Year Published: 2022

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