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Therapy‐induced senescent cancer cells increase the expression of the cyclin‐dependent kinase inhibitors p16Ink4a and p21Cip1/Waf1. Given that p21 regulates not only the cell cycle but also cell death, we investigated… Click to show full abstract
Therapy‐induced senescent cancer cells increase the expression of the cyclin‐dependent kinase inhibitors p16Ink4a and p21Cip1/Waf1. Given that p21 regulates not only the cell cycle but also cell death, we investigated the roles of p21 in cell death using a p16‐negative A549 human lung adenocarcinoma cell line.
Keywords:
p21cip1 waf1;
protective roles;
lung;
roles cytoplasmic;
cancer cells
Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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Journal Title: Cell Proliferation
Year Published: 2022
Link to full text (if available)
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recommendations!