IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations… Click to show full abstract
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We aim to underscore the potential of IMPDH2 as a promising therapeutic target for clinical applications.
Keywords:
role cellular;
cellular growth;
central role;
target;
impdh2 central;
therapeutic target
Journal Title: Cell Proliferation
Year Published: 2025
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Journal Title: Cell Proliferation
Year Published: 2025
Link to full text (if available)
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recommendations!