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The association of pregnane X receptor activation with outcomes after liver transplantation—A retrospective study

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Many complications following liver transplantation are linked to ischemia‐reperfusion injury. Activation of the pregnane X receptor (PXR) has been shown to alleviate this process in animal models. The aim of… Click to show full abstract

Many complications following liver transplantation are linked to ischemia‐reperfusion injury. Activation of the pregnane X receptor (PXR) has been shown to alleviate this process in animal models. The aim of this retrospective study was to investigate the effect of early activation of human PXR (hPXR) on postoperative complications and survival following liver transplantation.

Keywords: liver transplantation; transplantation; activation; pregnane receptor; retrospective study

Journal Title: Clinical Transplantation
Year Published: 2019

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