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Reducing cold ischemia time by donor liver “back‐table” preparation under continuous oxygenated machine perfusion of the portal vein

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Cold ischemia time is a well‐known risk factor for the development of non‐anastomotic biliary strictures (NAS) after liver transplantation. End‐ischemic hypothermic oxygenated machine perfusion (HOPE) of DCD liver grafts reduces… Click to show full abstract

Cold ischemia time is a well‐known risk factor for the development of non‐anastomotic biliary strictures (NAS) after liver transplantation. End‐ischemic hypothermic oxygenated machine perfusion (HOPE) of DCD liver grafts reduces the incidence of NAS, and has the potential to reduce cold ischemia times. We hypothesized that if a part of the back‐table procedure could be performed under continuous HOPE, cold ischemia times would be reduced.

Keywords: ischemia; liver; cold ischemia; ischemia time; machine perfusion; oxygenated machine

Journal Title: Clinical Transplantation
Year Published: 2022

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