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Pharmacotherapy of chronic lung allograft dysfunction post lung transplantation

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Chronic lung allograft dysfunction (CLAD) remains the primary cause of death in lung transplant recipients (LTRs) despite improvements in immunosuppression management. Despite advances in knowledge regarding the pathogenesis of CLAD,… Click to show full abstract

Chronic lung allograft dysfunction (CLAD) remains the primary cause of death in lung transplant recipients (LTRs) despite improvements in immunosuppression management. Despite advances in knowledge regarding the pathogenesis of CLAD, treatments that are currently available are usuallyineffective and delay progression of disease at best.There are currently no evidenceā€based guidelines and minimal publications regarding the optimal treatment ofCLAD.

Keywords: lung; lung allograft; chronic lung; allograft dysfunction

Journal Title: Clinical Transplantation
Year Published: 2022

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