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Automated scoring of total inflammation in renal allograft biopsies

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Computer‐assisted scoring is gaining prominence in the evaluation of renal histology; however, much of the focus has been on identifying larger objects such as glomeruli. Total inflammation impacts graft outcome,… Click to show full abstract

Computer‐assisted scoring is gaining prominence in the evaluation of renal histology; however, much of the focus has been on identifying larger objects such as glomeruli. Total inflammation impacts graft outcome, and its quantification requires tools to identify objects at the cellular level or smaller. The goal of the current study was to use CD45 stained slides coupled with image analysis tools to quantify the amount of non‐glomerular inflammation within the cortex.

Keywords: inflammation; automated scoring; total inflammation; scoring total; renal allograft; inflammation renal

Journal Title: Clinical Transplantation
Year Published: 2022

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