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Critical need for pharmacologic treatment options in NAFLD: A pediatric perspective

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Nonalcoholic fatty liver disease (NAFLD) affects up to 70% of children with obesity and has become the number one etiology for liver transplant in the United States. Early, effective intervention… Click to show full abstract

Nonalcoholic fatty liver disease (NAFLD) affects up to 70% of children with obesity and has become the number one etiology for liver transplant in the United States. Early, effective intervention is critical to prevent disease progression into adulthood. Yet, it is seldom achieved through lifestyle modification alone. Thus, children must be included in NAFLD pharmacology trials, which, to date, continue to focus primarily on adult populations. This commentary serves as a call to action.

Keywords: pharmacologic treatment; critical need; treatment options; options nafld; need pharmacologic; nafld pediatric

Journal Title: Clinical and Translational Science
Year Published: 2021

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