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Aneurysmal fibrous histiocytomas with recurrent rearrangement of the PRKCD gene and LAMTOR1‐PRKCD fusions

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Aneurysmal fibrous histiocytoma (FH) is an uncommon variant of cutaneous benign fibrous histiocytoma/dermatofibroma1 typically presenting as a solitary, pigmented, up to several centimeters in size nodule on extremities or trunk… Click to show full abstract

Aneurysmal fibrous histiocytoma (FH) is an uncommon variant of cutaneous benign fibrous histiocytoma/dermatofibroma1 typically presenting as a solitary, pigmented, up to several centimeters in size nodule on extremities or trunk of middle-aged adults.1,2 Some cases may be clinically concerning for melanoma or vascular neoplasia.1 The local recurrence rate is ~20%, if incompletely excised.1 This article is protected by copyright. All rights reserved.

Keywords: recurrent rearrangement; rearrangement prkcd; aneurysmal fibrous; prkcd; histiocytomas recurrent; fibrous histiocytomas

Journal Title: Journal of Cutaneous Pathology
Year Published: 2018

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