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Paraneoplastic pemphigus: Revised diagnostic criteria based on literature analysis

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Paraneoplastic pemphigus (PNP) is a rare autoimmune bullous disease classically associated with an underlying neoplasm. The heterogeneous clinical and histopathologic features of the disease make diagnosis challenging for clinicians. There… Click to show full abstract

Paraneoplastic pemphigus (PNP) is a rare autoimmune bullous disease classically associated with an underlying neoplasm. The heterogeneous clinical and histopathologic features of the disease make diagnosis challenging for clinicians. There are no formally accepted diagnostic criteria, and newer techniques for identifying antibodies directed against plakin proteins have largely replaced immunoprecipitation, the historic gold standard.

Keywords: criteria based; pemphigus revised; revised diagnostic; diagnostic criteria; paraneoplastic pemphigus

Journal Title: Journal of Cutaneous Pathology
Year Published: 2021

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