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PRAME immunohistochemistry for melanoma diagnosis: A STARD‐compliant diagnostic accuracy study

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Preferentially expressed antigen in melanoma (PRAME) is a tumor‐associated antigen that is frequently expressed in cutaneous melanoma and can be evaluated by immunohistochemistry. Earlier studies on PRAME utilized case‐control study… Click to show full abstract

Preferentially expressed antigen in melanoma (PRAME) is a tumor‐associated antigen that is frequently expressed in cutaneous melanoma and can be evaluated by immunohistochemistry. Earlier studies on PRAME utilized case‐control study designs that may misestimate diagnostic accuracy and lack generalizability.

Keywords: prame; immunohistochemistry; melanoma; diagnostic accuracy; study

Journal Title: Journal of Cutaneous Pathology
Year Published: 2022

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