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BRCA1‐associated protein 1 (BAP‐1) is a deubiquitylase that functions as a tumor suppressor, regulating multiple cellular processes including cell cycle control, differentiation, cell death, and DNA repair. BAP‐1‐inactivated melanocytic tumors… Click to show full abstract
BRCA1‐associated protein 1 (BAP‐1) is a deubiquitylase that functions as a tumor suppressor, regulating multiple cellular processes including cell cycle control, differentiation, cell death, and DNA repair. BAP‐1‐inactivated melanocytic tumors (BIMTs) have recently been described and are characterized by epithelioid cytomorphology, are often clonal in appearance, and typically do not recur or show malignant transformation on follow‐up.
Keywords:
bap;
molecular characterization;
inactivated melanoma;
histopathologic molecular;
bap inactivated;
characterization bap
Journal Title: Journal of Cutaneous Pathology
Year Published: 2022
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Journal Title: Journal of Cutaneous Pathology
Year Published: 2022
Link to full text (if available)
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recommendations!