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The cytological diagnosis of follicular‐patterned thyroid lesions is challenging, especially since the World Health Organisation classification has recognised non‐invasive follicular thyroid neoplasm with papillary‐like features. These entities are often classified… Click to show full abstract
The cytological diagnosis of follicular‐patterned thyroid lesions is challenging, especially since the World Health Organisation classification has recognised non‐invasive follicular thyroid neoplasm with papillary‐like features. These entities are often classified as indeterminate on cytology. Molecular testing has been proposed to help classify indeterminate nodules. RAS and K601E BRAF mutations are mostly encountered in follicular‐patterned lesions, but their diagnostic value is not well established. Nuclear scores have also been proposed to help classify indeterminate lesions.
Journal Title: Cytopathology
Year Published: 2020
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