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Effects of the menstrual cycle on cytological false‐negatives in women with persistent cervical intraepithelial neoplasia

False‐negatives on cytology may be observed during follow‐ups for patients with persistent cervical intraepithelial neoplasia (CIN); however, the underlying reasons are unknown, and the relationship between the intra‐individual variability of… Click to show full abstract

False‐negatives on cytology may be observed during follow‐ups for patients with persistent cervical intraepithelial neoplasia (CIN); however, the underlying reasons are unknown, and the relationship between the intra‐individual variability of false‐negatives and the menstrual cycle phase has not been elucidated. Therefore, this study aimed to determine whether the menstrual cycle influences cytological results to maximise the accuracy of such tests.

Keywords: persistent cervical; menstrual cycle; intraepithelial neoplasia; cervical intraepithelial; false negatives

Journal Title: Cytopathology
Year Published: 2022

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