Early‐stage gastric cancer (EGC) found after Helicobacter pylori (Hp) eradication often displays non‐tumorous regenerative epithelium and/or maturated tumorous epithelium overlying the cancerous tissue, which may confuse endoscopic and histological diagnosis.… Click to show full abstract
Early‐stage gastric cancer (EGC) found after Helicobacter pylori (Hp) eradication often displays non‐tumorous regenerative epithelium and/or maturated tumorous epithelium overlying the cancerous tissue, which may confuse endoscopic and histological diagnosis. Probe‐based confocal laser endomicroscopy (pCLE) enables in vivo real‐time optical biopsy. We compared the diagnostic yields for these EGC cases using conventional white light endoscopy (WL), magnifying endoscopy with narrow‐band imaging (ME‐NBI), pCLE, and endoscopic biopsy; we also compared the accuracy of the horizontal extent diagnosis between ME‐NBI and pCLE.
               
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