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Developmental outcomes after early surgery for complex congenital heart disease: a systematic review and meta‐analysis

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(1) To systematically review the literature on developmental outcomes from infancy to adolescence of children with complex congenital heart disease (CHD) who underwent early surgery; (2) to run a meta‐regression… Click to show full abstract

(1) To systematically review the literature on developmental outcomes from infancy to adolescence of children with complex congenital heart disease (CHD) who underwent early surgery; (2) to run a meta‐regression analysis on the Bayley Scales of Infant Development, Second Edition Mental Developmental Index and Psychomotor Developmental Index (PDI) of infants up to 24 months and IQs of preschool‐aged children to adolescents; (3) to assess associations between perioperative risk factors and outcomes.

Keywords: complex congenital; heart disease; early surgery; congenital heart; developmental outcomes

Journal Title: Developmental Medicine and Child Neurology
Year Published: 2020

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