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An alternative approach to modelling HbA1c trajectories in patients with type 2 diabetes mellitus

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Time‐dependent HbA1c trajectories in health economic models of type 2 diabetes mellitus (T2DM) are typically informed by the UK Prospective Diabetes Study (UKPDS). However, this approach may not accurately predict… Click to show full abstract

Time‐dependent HbA1c trajectories in health economic models of type 2 diabetes mellitus (T2DM) are typically informed by the UK Prospective Diabetes Study (UKPDS). However, this approach may not accurately predict HbA1c progression in patients who do not conform to the demographic profile of the original UKPDS cohort. This study aimed to develop an alternative mathematical model (MM) to simulate HbA1c progression in T2DM.

Keywords: alternative approach; approach modelling; type diabetes; diabetes mellitus; hba1c trajectories

Journal Title: Diabetes
Year Published: 2017

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