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Glucose‐lowering effects and mechanisms of the bile acid‐sequestering resin sevelamer

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Sevelamer, a non‐absorbable amine‐based resin used for treatment of hyperphosphataemia, has been demonstrated to have a marked bile acid‐binding potential alongside beneficial effects on lipid and glucose metabolism. The aim… Click to show full abstract

Sevelamer, a non‐absorbable amine‐based resin used for treatment of hyperphosphataemia, has been demonstrated to have a marked bile acid‐binding potential alongside beneficial effects on lipid and glucose metabolism. The aim of this study was to investigate the glucose‐lowering effect and mechanism(s) of sevelamer in patients with type 2 diabetes.

Keywords: sevelamer; resin; effects mechanisms; bile acid; lowering effects; glucose lowering

Journal Title: Diabetes
Year Published: 2018

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