Obesity, driven by complex genetic and environmental interactions, remains a global health crisis with limited therapeutic options. The insulin‐like growth factor 1 receptor (IGF1R) plays dual roles in metabolism and… Click to show full abstract
Obesity, driven by complex genetic and environmental interactions, remains a global health crisis with limited therapeutic options. The insulin‐like growth factor 1 receptor (IGF1R) plays dual roles in metabolism and growth, but its tissue‐specific functions in adipose biology are controversial. This study investigates how adipose‐specific IGF1R knockout impacts systemic metabolism under high‐fat diet (HFD) stress and explores the underlying mechanisms.
Keywords:
igf1r;
knockout activates;
adipocyte specific;
igf1r knockout;
specific igf1r
Journal Title: Diabetes
Year Published: 2025
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Journal Title: Diabetes
Year Published: 2025
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!