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The elevated level of osteopontin in patients with pemphigus vulgaris: A cytokine‐like protein with a therapeutic potential

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Pemphigus vulgaris (PV) is a life‐threatening autoimmune disease with no certain treatment. Anticytokine therapy is being increasingly discussed in multiple autoimmune diseases. Osteopontin (OPN) is a glycoprotein produced by a… Click to show full abstract

Pemphigus vulgaris (PV) is a life‐threatening autoimmune disease with no certain treatment. Anticytokine therapy is being increasingly discussed in multiple autoimmune diseases. Osteopontin (OPN) is a glycoprotein produced by a variety of immune cells. Increased OPN serum levels have been reported in several autoimmune diseases, with targeting OPN considered as a promising therapy in these diseases. However, the role of OPN in PV has not been well studied so far.

Keywords: pemphigus vulgaris; elevated level; patients pemphigus; osteopontin patients; vulgaris cytokine; level osteopontin

Journal Title: Dermatologic Therapy
Year Published: 2019

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