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Repurposing super saturated potassium iodide as an adjunctive treatment in mucormycosis: An exposition in a diabetic patient with rhino‐orbital disease with cutaneous extension

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Dear Editor, Mucormycosis has experienced a resurgence due to the use of immunosuppressive therapy and diabetes mellitus (DM). The treatment is challenging as it is limited by cost and availability… Click to show full abstract

Dear Editor, Mucormycosis has experienced a resurgence due to the use of immunosuppressive therapy and diabetes mellitus (DM). The treatment is challenging as it is limited by cost and availability of drugs like liposomal amphotericin B. A 54-year-old female with DM presented to the ENT outpatient department with complaints of nasal stuffiness, discharge, and left sided headache of 4 weeks duration. There was concomitant swelling over left side of face, watering from the left eye, diminished vision, history of difficulty in swallowing, left sided ear fullness, and right sided deviation of face with pain in left upper molar teeth. There was coexistent hypertension and hypothyroidism. There was no history of COVID-19 infection. Oral examination revealed ulceration over left side of palate covered with slough (Figure 1A), poor dental hygiene with left sided facial palsy. Eye examination revealed periorbital edema, total ophthalmoplegia of left eye with ptosis, absent perception of light (PL), congested conjunctiva with fixed and dilated pupils. Contrast enhanced computed tomography (CECT) of the nose and paranasal sinuses revealed curvilinear hyper densities occupying the sinuses and nasal endoscopy confirmed inflammation of inferior turbinates and presence of yellowish-brown discharge which on histopathology revealed few broad, aseptate fungal hyphae suggestive of

Keywords: mucormycosis; treatment; repurposing super; left sided; saturated potassium; super saturated

Journal Title: Dermatologic Therapy
Year Published: 2021

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