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Pulsed dye laser prior to CO2 laser ablation to treat multiple cutaneous neurofibromas in von Recklinghausen's disease: A case report

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one the most disorders. large numbers of cutaneous neurofibromas by excision is exceedingly time-con-suming, costly, and at risk of scarring. 2 laser ablation is an alternative to surgical excision that… Click to show full abstract

one the most disorders. large numbers of cutaneous neurofibromas by excision is exceedingly time-con-suming, costly, and at risk of scarring. 2 laser ablation is an alternative to surgical excision that has become the standard treatment for removing hundreds of neurofibromas with minimal blood loss, but resulting in depigmented scars. 1 This risk is reduced thanks to the use of the pulsed dye laser (PDL). We present the case of a 65-year-old female patient with Fitzpatrick skin phototype II, suffering from multiple neurofibromas all over the skin surface. The patient was treated with a PDL/CO 2 laser ablation combination therapy from May 2015 to early 2019. For larger neurofibromas, PDL laser was performed 2 weeks prior to CO 2 vaporizations and immediately after as intralesional vaporization treatment to minimize scarring. For the small ones, PDL was performed as standalone technique. The PDL (Synchro VasQ – DEKA) has been used with these parameters: 12 mm size spot, fluence 4 – 7 J/cm 2 , and fre-quency 0.5/s. We used a CO 2 laser (Punto, DEKA) with a focused beam of 0.1 – 0.2 mm diameter, power 0.5 – 4 W. It was not necessary to apply sutures because of the vaporization of the tissues, and the wound was only medicated for a few days and then left uncovered. The patient was given systemic antibiotic therapy after each treatment.

Keywords: cutaneous neurofibromas; pulsed dye; laser ablation; ablation; dye laser

Journal Title: Dermatologic Therapy
Year Published: 2022

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