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Circadian regulation of neutrophils: Control by a cell‐autonomous clock or systemic factors?

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The circadian time‐measuring system enables the organism to anticipate and effectively respond to regular daily changes in the environment and is therefore a crucial factor of adaptation. A large body… Click to show full abstract

The circadian time‐measuring system enables the organism to anticipate and effectively respond to regular daily changes in the environment and is therefore a crucial factor of adaptation. A large body of epidemiological data underlines the circadian characteristics of human immune functions. Circadian control of neutrophil responsiveness contributes to daily changes in the pathology of both acute and chronic inflammation and may therefore time‐dependently influence the outcome of therapeutic approaches.

Keywords: neutrophils control; circadian regulation; regulation neutrophils; control; control cell; cell autonomous

Journal Title: European Journal of Clinical Investigation
Year Published: 2018

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