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Neutrophil recruitment during acute inflammation critically depends on the spatial and temporal regulation of β2 integrins (CD11/CD18). This regulation occurs by inside‐out and outside‐in signalling via interaction of cytoplasmic proteins… Click to show full abstract
Neutrophil recruitment during acute inflammation critically depends on the spatial and temporal regulation of β2 integrins (CD11/CD18). This regulation occurs by inside‐out and outside‐in signalling via interaction of cytoplasmic proteins with the intracellular domains of the integrin α‐ and β‐subunits. The underlying molecular mechanisms regulating β2 integrins in neutrophils are still incompletely understood.
Keywords:
partners neutrophil;
cd18 interacting;
integrin cd11;
cd11 cd18;
interacting partners;
intracellular integrin
Journal Title: European Journal of Clinical Investigation
Year Published: 2018
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Journal Title: European Journal of Clinical Investigation
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!