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Several recent studies suggest a possible role of lymphocyte activation 3 (LAG3) protein. LAG3 can behave as an α‐synuclein ligand, and serum and cerebrospinal fluid‐soluble LAG3 levels have been proposed… Click to show full abstract
Several recent studies suggest a possible role of lymphocyte activation 3 (LAG3) protein. LAG3 can behave as an α‐synuclein ligand, and serum and cerebrospinal fluid‐soluble LAG3 levels have been proposed as a marker of Parkinson's disease (PD). In this study, we aimed to investigate whether there is an association between 3 common single‐nucleotide variations (SNVs) in the LAG3 gene and its closely related CD4 molecule gene and the risk of PD in a Caucasian Spanish population. Two of them have been previously associated with the risk of PD in Chinese females.
Journal Title: European Journal of Clinical Investigation
Year Published: 2022
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