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The influence of hypoxia‐mediated CEACAM6 upregulation on epithelial cell and macrophage response in the context of gastric cancer

The hypoxic microenvironment is a key component of the gastric tumour niche. Carcinoembryonic antigen‐related cell adhesion molecule 6 (CEACAM6) is upregulated in gastric cancer and is considered a novel biomarker… Click to show full abstract

The hypoxic microenvironment is a key component of the gastric tumour niche. Carcinoembryonic antigen‐related cell adhesion molecule 6 (CEACAM6) is upregulated in gastric cancer and is considered a novel biomarker for the disease. However, no prior studies have elaborated on the status of CEACAM6 and its role in the hypoxic gastric cancer niche.

Keywords: cancer; gastric cancer; mediated ceacam6; cell; hypoxia mediated; influence hypoxia

Journal Title: European Journal of Clinical Investigation
Year Published: 2024

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