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It is well established that expression of multi‐drug resistance (MDR) proteins (MDR1, BCRP, MDR3, MRP1, and LRP) in leukemic blasts correlates with acute myeloid leukemia (AML) patients’ clinical response. Assuming… Click to show full abstract
It is well established that expression of multi‐drug resistance (MDR) proteins (MDR1, BCRP, MDR3, MRP1, and LRP) in leukemic blasts correlates with acute myeloid leukemia (AML) patients’ clinical response. Assuming that leukemic stem cells (LSC) are resistant to chemotherapy and responsible for relapse, it might be clinically relevant to evaluate the expression level of MDR proteins in LSC and relate it to the clinical outcome.
Keywords:
myeloid leukemia;
leukemic stem;
expression;
acute myeloid;
stem cells
Journal Title: European Journal of Haematology
Year Published: 2017
Link to full text (if available)
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Journal Title: European Journal of Haematology
Year Published: 2017
Link to full text (if available)
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recommendations!