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Cobalamin, or vitamin B12, is used as a cofactor in a wide range of enzymatic reactions, including the regulation of homocysteine levels and DNA synthesis. Under physiologic circumstances, approximately 80%… Click to show full abstract
Cobalamin, or vitamin B12, is used as a cofactor in a wide range of enzymatic reactions, including the regulation of homocysteine levels and DNA synthesis. Under physiologic circumstances, approximately 80% of the serum cobalamin is bound to haptocorrin, whilst 20% is bound to transcobalamin. The latter protein facilitates the cellular uptake of cobalamin where it can perform its function.
Keywords:
hypercobalaminemia myeloid;
lymphoid malignancies;
myeloid lymphoid
Journal Title: European Journal of Haematology
Year Published: 2019
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Journal Title: European Journal of Haematology
Year Published: 2019
Link to full text (if available)
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recommendations!