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Integrin expression and adhesivity to fibronectin in primary acute myeloid leukemia cells: Impact of NPM1 and FLT3 mutations

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Interaction of leukemia cells with the bone marrow extracellular matrix promotes cell survival and resistance to chemotherapy. In this work, we analyzed integrin expression and adhesivity to fibronectin in primary… Click to show full abstract

Interaction of leukemia cells with the bone marrow extracellular matrix promotes cell survival and resistance to chemotherapy. In this work, we analyzed integrin expression and adhesivity to fibronectin in primary cells from patients with acute myeloid leukemia.

Keywords: integrin expression; leukemia cells; adhesivity fibronectin; expression adhesivity; fibronectin primary; acute myeloid

Journal Title: European Journal of Haematology
Year Published: 2020

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