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The interval between frontline treatment and the second relapse (PFS2) predicts survival from the second relapse in follicular lymphoma patients

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Follicular lymphoma (FL) is the most frequent indolent B-cell lymphoma. The introduction of immunotherapy has greatly improved outcomes for FL patients, with a median overall survival (OS) now approaching 20… Click to show full abstract

Follicular lymphoma (FL) is the most frequent indolent B-cell lymphoma. The introduction of immunotherapy has greatly improved outcomes for FL patients, with a median overall survival (OS) now approaching 20 years. However, relapses are continuously seen during follow-up, and responses progressively shorten with each relapse, with a median survival after third-line therapy of 4.8 years.

Keywords: follicular lymphoma; relapse; frontline treatment; second relapse; interval frontline

Journal Title: European Journal of Haematology
Year Published: 2020

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