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Accumulating studies show that the tumour suppressor SOCS1 is one of the most frequently mutated genes in lymphomas, often affecting the coding sequence of SOCS1 protein. Depending on the type… Click to show full abstract
Accumulating studies show that the tumour suppressor SOCS1 is one of the most frequently mutated genes in lymphomas, often affecting the coding sequence of SOCS1 protein. Depending on the type of mutation and lymphoma concerned, SOCS1 mutations have different impacts on progression‐free and overall survival. Two antibodies binding the N and C terminals of SOCS1 would be a suitable ‘test pair’ to identify truncated versions of SOCS1. We, therefore, compared the C‐terminal antibody 424C with the N‐terminal antibody 4H1.
Keywords:
antibodies socs1;
combination two;
two monoclonal;
terminal binding;
socs1 terminal;
monoclonal antibodies
Journal Title: European Journal of Haematology
Year Published: 2021
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Journal Title: European Journal of Haematology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!