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Advanced clinical parameters: A complementary hydroxyurea adherence evaluation in sickle cell anemia treatment

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Given the complex pathology of sickle cell anemia (SCA) and low adherence to hydroxyurea (HU) treatment, there is a need to seek parameters that identify recent changes in patient status.… Click to show full abstract

Given the complex pathology of sickle cell anemia (SCA) and low adherence to hydroxyurea (HU) treatment, there is a need to seek parameters that identify recent changes in patient status. The advanced clinical parameters (ACPs) allow an early analysis of hematopoiesis. We aimed to draw the demographic profile of non‐adherent SCA patients and to verify the use of ACPs as a measure of HU treatment adherence.

Keywords: cell anemia; adherence; advanced clinical; clinical parameters; treatment; sickle cell

Journal Title: European Journal of Haematology
Year Published: 2022

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