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Assessment of bulbar function in amyotrophic lateral sclerosis: validation of a self‐report scale (Center for Neurologic Study Bulbar Function Scale)

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Impaired bulbar functions of speech and swallowing are among the most serious consequences of amyotrophic lateral sclerosis (ALS). Despite this, clinical trials in ALS have rarely emphasized bulbar function as… Click to show full abstract

Impaired bulbar functions of speech and swallowing are among the most serious consequences of amyotrophic lateral sclerosis (ALS). Despite this, clinical trials in ALS have rarely emphasized bulbar function as an endpoint. The rater‐administered Amyotrophic Lateral Sclerosis Functional Rating Scale‐Revised (ALSFRS‐R) or various quality‐of‐life measures are commonly used to measure symptomatic benefit. Accordingly, we sought to evaluate the utility of measures specific to bulbar function in ALS.

Keywords: bulbar; bulbar function; amyotrophic lateral; lateral sclerosis

Journal Title: European Journal of Neurology
Year Published: 2018

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