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Clopidogrel may decrease the risk of post‐stroke infection after ischaemic stroke

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The P2Y12 receptor, a well‐known factor in the platelet activation pathway, plays a role in thrombosis as well as systemic inflammation. Clopidogrel, a prototype P2Y12 receptor antagonist, reportedly decreases inflammation… Click to show full abstract

The P2Y12 receptor, a well‐known factor in the platelet activation pathway, plays a role in thrombosis as well as systemic inflammation. Clopidogrel, a prototype P2Y12 receptor antagonist, reportedly decreases inflammation and systemic infection. The aim of this study was to evaluate whether clopidogrel use decreases the risk of post‐stroke infection following ischaemic stroke.

Keywords: post stroke; stroke infection; clopidogrel; risk post; infection; ischaemic stroke

Journal Title: European Journal of Neurology
Year Published: 2019

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