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Abnormal α‐synuclein deposits in skin nerves: intra‐ and inter‐laboratory reproducibility

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Visualization of phosphorylated α‐synuclein at serine 129 (p‐syn) in skin nerves is a promising test for the in vivo diagnosis of synucleinopathies. Here the aim was to establish the intra‐… Click to show full abstract

Visualization of phosphorylated α‐synuclein at serine 129 (p‐syn) in skin nerves is a promising test for the in vivo diagnosis of synucleinopathies. Here the aim was to establish the intra‐ and inter‐laboratory reproducibility of measurement of intraneural p‐syn immunoreactivity in two laboratories with major expertise (Würzburg and Bologna).

Keywords: laboratory reproducibility; skin nerves; intra inter; inter laboratory

Journal Title: European Journal of Neurology
Year Published: 2019

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