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Intravenous (IV) lysis with alteplase is known to increase biomarkers of blood–brain barrier breakdown and has therefore been associated with secondary injuries such as hemorrhagic transformation. The impact of alteplase… Click to show full abstract
Intravenous (IV) lysis with alteplase is known to increase biomarkers of blood–brain barrier breakdown and has therefore been associated with secondary injuries such as hemorrhagic transformation. The impact of alteplase on brain edema formation, however, has not been investigated yet. The purpose was to examine the effects of IV alteplase on ischaemic lesion water homeostasis differentiated from final tissue infarct in patients with and without successful endovascular therapy (sET).
Keywords:
lesion water;
ischaemic lesion;
alteplase ischaemic;
water homeostasis;
alteplase
Journal Title: European Journal of Neurology
Year Published: 2019
Link to full text (if available)
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Journal Title: European Journal of Neurology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!