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Familial clustering of primary lateral sclerosis and amyotrophic lateral sclerosis: Supplementary evidence for a continuum.

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In their article, Corcia et al. describe a series of 9 patients suffering from primary lateral sclerosis (PLS) coming from different family clusters, in which every individual had a first-… Click to show full abstract

In their article, Corcia et al. describe a series of 9 patients suffering from primary lateral sclerosis (PLS) coming from different family clusters, in which every individual had a first- or second-degree relative affected by amyotrophic lateral sclerosis (ALS). The authors concluded from their results, that adult-onset PLS might be an inherited disease, and that there was a continuum between PLS and ALS, as both diseases coexisted in the reported kinships [1].

Keywords: primary lateral; sclerosis; continuum; amyotrophic lateral; familial clustering; lateral sclerosis

Journal Title: European journal of neurology
Year Published: 2021

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