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Abnormal mitochondrial metabolism has been described in the Alzheimer's disease (AD) brain. However, the relationship between AD pathophysiology and key mitochondrial processes remains elusive. The purpose of this study was… Click to show full abstract
Abnormal mitochondrial metabolism has been described in the Alzheimer's disease (AD) brain. However, the relationship between AD pathophysiology and key mitochondrial processes remains elusive. The purpose of this study was to investigate whether mitochondrial complex I dysfunction is associated with amyloid aggregation or glucose metabolism and brain atrophy in patients with mild AD using positron emission tomography (PET).
Keywords:
mitochondrial complex;
underlie neurodegeneration;
alzheimer disease;
abnormalities underlie;
complex abnormalities
Journal Title: European Journal of Neurology
Year Published: 2022
Link to full text (if available)
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Journal Title: European Journal of Neurology
Year Published: 2022
Link to full text (if available)
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recommendations!