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CCR5‐Δ32 polymorphism—a possible protective factor from gait impairment amongst post‐stroke patients

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Stroke and small vessel disease cause gait disturbances and falls. The naturally occurring loss‐of‐function mutation in the C‐C chemokine receptor 5 gene (CCR5‐Δ32) has recently been reported as a protective… Click to show full abstract

Stroke and small vessel disease cause gait disturbances and falls. The naturally occurring loss‐of‐function mutation in the C‐C chemokine receptor 5 gene (CCR5‐Δ32) has recently been reported as a protective factor in post‐stroke motor and cognitive recovery. We sought to examine whether it also influences gait and balance measures up to 2 years after stroke.

Keywords: ccr5 polymorphism; post stroke; protective factor; gait

Journal Title: European Journal of Neurology
Year Published: 2022

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