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Association of regional white matter hyperintensities with hypertension and cognition in the population‐based 1000BRAINS study

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White matter hyperintensities of presumed vascular origin (WMH) are frequent in cerebral magnetic resonance imaging of older people. They are promoted by vascular risk factors, especially hypertension, and are associated… Click to show full abstract

White matter hyperintensities of presumed vascular origin (WMH) are frequent in cerebral magnetic resonance imaging of older people. They are promoted by vascular risk factors, especially hypertension, and are associated with cognitive deficits at the group level. It has been suggested that not only the severity, but also the location, of lesions might critically influence cognitive deficits and represent different pathologies.

Keywords: white matter; hyperintensities hypertension; regional white; matter hyperintensities; association regional

Journal Title: European Journal of Neurology
Year Published: 2023

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