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Substantia nigra degeneration in spinocerebellar ataxia 2 and 7 using neuromelanin‐sensitive imaging

Spinocerebellar ataxias (SCA) are neurodegenerative diseases with widespread lesions across the central nervous system. Ataxia and spasticity are usually predominant, but patients may also present with parkinsonism. We aimed to… Click to show full abstract

Spinocerebellar ataxias (SCA) are neurodegenerative diseases with widespread lesions across the central nervous system. Ataxia and spasticity are usually predominant, but patients may also present with parkinsonism. We aimed to characterize substantia nigra pars compacta (SNc) degeneration in SCA2 and 7 using neuromelanin‐sensitive imaging.

Keywords: using neuromelanin; sensitive imaging; neuromelanin sensitive; degeneration; substantia nigra

Journal Title: European Journal of Neurology
Year Published: 2025

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